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Neurological

Sleep Disorders

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Sleep Disorders

Understanding Sleep Disorders

Introduction to Sleep Disorders

Sleep is an important part of our health, but for some people, getting good sleep is a challenge. Sleep disorders are conditions that make it hard to fall asleep, stay asleep, or feel rested even after a full night’s sleep. People with sleep disorders may feel very tired during the day, have trouble staying awake, or struggle to complete daily tasks. These disorders can make school, work, and social life more difficult.

Sleep disorders, such as narcolepsy, idiopathic hypersomnia (IH), and other conditions that cause excessive sleepiness, may follow seasonal patterns. Some people notice that their symptoms get worse in certain times of the year, such as late winter to late spring.

Causes and Risk Factors

There are many different sleep disorders, and each one has different causes. Some common types of sleep disorders include:

  • Narcolepsy Type 1 (NT1) and Type 2 (NT2): People with NT1 have extreme daytime sleepiness and may have sudden muscle weakness, called cataplexy. NT2 is similar, but without cataplexy.
  • Idiopathic Hypersomnia (IH): People with IH sleep for long hours but still feel tired. Even after getting extra sleep, they may struggle to wake up and feel refreshed.
  • Other Hypersomnolence Disorders: These conditions cause chronic sleepiness but may not have a clear cause.
  • Scientists are still studying what causes these sleep disorders, but some possible factors include:
  • Genetics: Some sleep disorders run in families, meaning a person is more likely to develop one if a close relative has it.
  • Brain Injury: Damage to parts of the brain that control sleep can sometimes lead to sleep disorders.
  • Immune System Problems: In some cases, the body’s immune system mistakenly attacks brain cells that help control wakefulness. This is believed to be a cause of NT1.
  • Chemical Imbalances in the Brain: People with NT1 have low levels of hypocretin, a brain chemical that helps control sleep and wakefulness.

Diagnosing Sleep Disorders 

Doctors use different tests to find out if someone has a sleep disorder. These may include:

  • Sleep Study (Polysomnography): This test measures brain activity, breathing, heart rate, and movement while a person sleeps.
  • Multiple Sleep Latency Test (MSLT): This test checks how quickly someone falls asleep during the day and if the individiual enters REM sleep too quickly, which can help diagnose narcolepsy.
  • Sleep Diary: Patients may be asked to track their sleep patterns and symptoms for a few weeks. 

Current Treatment Options for Sleep Disorders 

There is no cure for most sleep disorders, but treatment can help manage symptoms. Some options include:

  • Medications: Some medicines help people stay awake during the day, while others improve nighttime sleep.
  • Lifestyle Changes: Sticking to a regular sleep schedule, taking short naps, and avoiding caffeine before bed can help improve sleep quality.
  • Cognitive Behavioral Therapy (CBT): This therapy helps people change habits and thoughts that may be affecting their sleep. 

Living with a Sleep Disorder 

Having a sleep disorder can be frustrating and affect daily life. People may struggle to stay awake at work or school, and social activities can feel exhausting. It’s important to talk to family, friends, and teachers or employers about the condition so they can offer support. Finding ways to manage symptoms, such as planning naps and following a bedtime routine, can make a big difference. 

Sleep Disorder and Research and Progress 

Scientists are working hard to find better treatments for sleep disorders. Takeda is focused on research to develop new medicines that may help people with excessive daytime sleepiness and other sleep disorders.

Your experience with Sleep Disorder is valuable.

Sign up for our patient registry to gain more information on Takeda clinical trials aimed at improving the management of sleep disorders and discover how you might play a role in advancing sleep disorder research. Together, we can make a difference.

How WeConnect Works.

Takeda’s patient registry for clinical trials is a breeze to sign up for.

Click the 'Register' button.

Complete a brief contact information form.

Choose your areas of interest.

Look out for a confirmation email.

And just like that—you’re all set!

Now, you can relax while we keep you updated with notifications about Takeda’s clinical trials that might be just the right fit for you.

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Keep connecting.

We know you're interested in signing up for Takeda's WeConnect to get direct communication about Takeda clinical trials, but just in case you are looking for other ways to get involved – please review the information below.

Plasma donation.

Plasma-derived therapies are critical, life-saving medicines that many people with rare and complex diseases rely on. Global demand for plasma-derived products, mainly immunoglobulins, has increased dramatically in recent years.

BioLife Plasma Services is Takeda’s global plasma collection network and an industry leader in the collection of high-quality plasma that is processed into life-saving plasma-based therapies that benefit thousands of people every day.

 

Learn more about plasma donation and how to help people who require life-saving plasma-based therapies by donating your plasma.

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We at U.S. Medical Affairs at Takeda share your passion for science, evidence-based medicine, and commitment to promoting better health and brighter futures for our patients through potentially innovative medicines.

Our goal is to be readily available to support clinicians and researchers in whatever way we can. We believe the best way to improve disease outcomes is through robust and open communication about the science and clinical evidence.

 

That’s why we love to hear from medical professionals—to hear your questions, to understand what you’re seeing in the clinic, and to discuss research.

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